Polynucleotide vs HIFU: Advanced Skin Rejuvenation at Allens Aesthetics...
- allensaesthetics
- Jan 2
- 3 min read
At Allens Aesthetics, we specialise in advanced, non-surgical skin rejuvenation treatments designed to restore youthful vitality, firmness, and radiance. Two of our most effective treatments — Polynucleotide (PN) therapy and HIFU (High-Intensity Focused Ultrasound) — both target skin ageing, but in very different and complimentary ways.
Understanding how these treatments work can help you choose the best option or combination for your skin goals...
Polynucleotide Treatment: Skin Regeneration from Within
What is Polynucleotide Treatment?
Polynucleotide (PN) treatment involves injectable, naturally occurring DNA fragments, often derived from salmon, that stimulate cellular repair and regeneration within the skin.
How Does It Work?
Polynucleotides encourage your body to naturally produce:
Collagen
Elastin
Hyaluronic acid
This improves skin hydration, elasticity, and overall quality by working at a cellular level.
Best For:
Dull or tired-looking skin
Fine lines and early signs of ageing
Improving overall skin quality and hydration
Boosting radiance and texture
Treating acne scars and sun damage
Results:
Results appear gradually over several weeks, delivering subtle, natural-looking improvements. Skin becomes smoother, plumper, and more resilient — perfect for those seeking gentle rejuvenation rather than dramatic change.
HIFU (High-Intensity Focused Ultrasound): Deep Lifting & Tightening
What is HIFU?
HIFU is a non-surgical skin tightening treatment that uses focused ultrasound energy to target deeper layers of the skin.
How Does It Work?
HIFU delivers controlled heat to deep structural layers, including the SMAS layer — the same layer tightened during surgical facelifts. This heat causes tissue contraction and stimulates intense collagen production.
Best For:
Sagging skin and loss of firmness
Lifting jowls and jawline definition
Improving facial and neck contours
Deep collagen stimulation
Side Effects:
Immediately following the Doublo® treatment, the skin may appear red for a few hours. It is not uncommon to experience slight swelling for a few days and/or tingling and tenderness for up to 1 week following the procedure. These are mild and temporary and depend on the strength of the treatment and your personal reaction. You can calm the areas treated with ice packs for relief, 10 minutes out of every hour is advised. If there is swelling an extra pillow or two is advised. If some tiny red bands, or ‘cat scratches’ appear on the skin, this is nothing to worry about and can be treated with hydrocortisone cream. Ibuprofen cream can also help with inflammation. If you experience any other side effects or have any further concerns please contact us.
Results:
Patients often notice an initial tightening effect, with full results developing over 2–3 months as collagen rebuilds. Results are long-lasting, making HIFU an excellent option for those seeking a non-surgical facelift effect.
Before treatment & 2 months after treatment.
Combining Polynucleotides & HIFU for Optimal Results
Polynucleotide and HIFU treatments work beautifully together because they target different layers of the skin:
Polynucleotides improve skin quality, hydration, and cellular regeneration.
HIFU delivers deep lifting and tightening at a structural level.
When combined, they can produce firmer, smoother, and more lifted skin, offering comprehensive rejuvenation rather than treating just one concern. This approach is ideal for patients wanting both improved skin quality and visible lifting.
Which Treatment Is Right for You?
At Pure Aesthetics Nottingham, every treatment plan begins with a professional consultation to ensure your skin receives the right solution for your goals.
Choose Polynucleotides if your goal is overall skin rejuvenation, hydration, and texture improvement.
Choose HIFU if you’re concerned about sagging, laxity, and loss of facial definition.
Consider combination treatment for the most complete skin transformation.
For more information please contact us or book your appointment online.
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